The structure of the multiprotein Fanconi anaemia core complex, determined using cryo-electron microscopy and mass spectrometry, shows that the complex adopts an extended asymmetric structure and highlights the structural and functional asymmetry of the RING finger domains.
AlphaStar is the first AI to reach the top league of a widely popular esport without any game restrictions. This January, a preliminary version of AlphaStar challenged two of the world’s top players in StarCraft II, one of the most enduring and popular real-time strategy video games of all time. Since then, we have taken on a much greater challenge: playing the full game at a Grandmaster level under professionally approved conditions.
Our species likely arose in many places around Africa, not just around the Kalahari Desert, critics say
Findling, Skvortsova et al. find that a large fraction of non-greedy decisions that humans make in volatile environments do not stem from exploration but from the limited precision of learning, and further identify its neurophysiological correlates.
A contentious new paper traces the origins of modern humans to ancient wetlands in Africa, a claim other researchers have called far-fetched.
In artificial neural networks, the three components specified by design are the objective functions, the learning rules and the architectures. With the growing success of deep learning, which utilizes brain-inspired architectures, these three designed components have increasingly become central to how we model, engineer and optimize complex artificial learning systems. Here we argue that a greater focus on these components would also benefit systems neuroscience.
Our Sycamore processor takes about 200 seconds to sample one instance of a quantum circuit a million times—our benchmarks currently indicate that the equivalent task for a state-of-the-art classical supercomputer would take approximately 10,000 years
Here, we describe several methods by which an adversary who wants to learn the genotypes of people in the database can do so by uploading multiple datasets.
Science tells us that a lot of good things happen in our brains while we sleep—learning and memories are consolidated and waste is removed, among other things. New research shows for the first time that important immune cells called microglia—which play an important role in reorganizing the connections between nerve cells, fighting infections, and repairing damage—are also primarily active while we sleep.
We present structures of mouse TRPV3 in temperature-dependent open, closed and intermediate states that suggest two-step activation of TRPV3 by heat.