Respiratory disease and virus shedding in rhesus macaques inoculated with SARS-CoV-2 [Preprint]

Although data on disease in humans are emerging at a steady pace, certain aspects of the pathogenesis of SARS-CoV-2 can only be studied in detail in animal models, where repeated sampling and tissue collection is possible. Here, we show that SARS-CoV-2 causes respiratory disease in infected rhesus macaques, with disease lasting 8-16 days…

Taken together, the rhesus macaque recapitulates moderate disease observed in the majority of human cases. The establishment of the rhesus macaque as a model of COVID-19 will increase our understanding of the pathogenesis of this disease and will aid development and testing of medical countermeasures.

How the Virus Got Out

We analyzed the movements of hundreds of millions of people to show why the most extensive travel restrictions to stop an outbreak in human history haven’t been enough.